Abstract

Bioactive-stacked Nano-carriers represent a promising platform for targeted drug delivery and therapeutic applications. However, understanding the internal structure and dynamics of these Nano-carriers is crucial for optimizing their performance and efficacy. In this study, we employ Atomic Attractive Reverberation (NMR) spectroscopy as a powerful tool for unravelling the inner workings of bioactive-stacked Nano-carriers. By probing the atomic-level interactions within the Nano-carrier matrix, NMR spectroscopy provides valuable insights into the organization of bioactive molecules, the stability of the carrier structure, and the release kinetics of encapsulated payloads. Through a combination of experimental NMR measurements and computational modeling, we elucidate the structural features and dynamic behavior of bioactive-stacked Nano-carriers in solution. Our findings shed light on the mechanisms governing Nano-carrier function and provide a basis for the rational design of next-generation drug delivery systems with enhanced therapeutic capabilities.