Abstract

This longitudinal study investigates the neurodevelopmental basis of aggressive behavior in adolescents, aiming to elucidate the interplay between brain maturation and aggressive tendencies over time. Utilizing a multi-method approach, we assessed neurobiological markers, including structural MRI and functional connectivity analyses, alongside behavioral assessments of aggression. A cohort of 150 adolescents was followed from ages 12 to 18, with data collected at three key developmental stages. The results indicate that variations in brain structure, particularly in the prefrontal cortex and amygdala, significantly correlate with aggressive behaviors. Additionally, changes in neural connectivity patterns were linked to shifts in aggression levels throughout adolescence. These findings suggest that neurodevelopmental processes, particularly those related to emotional regulation and impulse control, play a crucial role in the manifestation of aggression during this critical developmental period. The study highlights the importance of considering neurobiological factors in understanding and addressing aggressive behavior in adolescents, offering implications for intervention strategies that focus on promoting healthy brain development.