Abstract

Multinucleated giant cells (MGCs) are intriguing cellular entities characterized by their distinctive morphology and diverse functions. Comprising multiple nuclei within a single cytoplasmic mass, MGCs play pivotal roles in various physiological processes and pathological conditions. This article provides a comprehensive overview of the anatomy, function, and clinical significance of MGCs. We explore their formation, mechanisms of action, and involvement in immune responses, bone remodeling, and disease pathology. Additionally, we discuss the diagnostic and therapeutic implications of MGCs in clinical practice, highlighting their importance as both markers of disease and potential therapeutic targets