Abstract

Dengue fever is a common arthropod-borne viral illness caused by the Dengue virus and transmitted by Aedes mosquitoes. Typically presenting with fever, headache, and musculoskeletal pain, severe cases can lead to lifethreatening complications. We report a unique case of Dengue fever with atypical neurological manifestations.

Case presentation: A 32-year-old healthy male presented with sudden high-grade fever, headache, and body aches. Diagnosed with Dengue fever, he developed neurological symptoms within 72 hours, including confusion, seizures, and weakness. Neuroimaging revealed cerebral edema, and cerebrospinal fluid analysis indicated viral meningitis with Dengue virus RNA. Managed with supportive care, fluid resuscitation, antivirals, and close monitoring, the patient showcased central nervous system involvement during Dengue infection.

Outcome: Despite aggressive management, the patient's neurological symptoms persisted, resulting in a prolonged hospital stay. This case underscores Dengue fever's potential for unusual complications like viral meningitis, emphasizing the importance of recognizing and addressing atypical presentations promptly for improved patient outcomes.

Conclusion: Dengue fever can manifest rare neurological complications, challenging clinicians to recognize diverse presentations, particularly in severe cases. Further research is needed to understand neurological involvement in Dengue and enhance treatment strategies.