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Case Report

Treatment of Medial and Lateral Elbow Tendinosis with an Injectable Amniotic Membrane Allograft a retrospective case series

Danielle Aufiero1*, Steven Sampson2, Kentaro Onishi3 and Angie Botto-van Bemden4
1The Orthohealing Center, Los Angeles, CA; David Geffen School of Medicine at UCLA, Los Angeles, CA; Western University of Health Sciences, Pomona CA; Touro University California, Vallejo, CA.
2The Orthohealing Center and The Orthobiologic Institute (TOBI), David Geffen School of Medicine at University of California Los Angeles, CA; 10780 Santa Monica Blvd, Suite 440, Los Angeles, CA 90025 Western University of Health Sciences, Pomona CA; Touro University California and Touro University New York, NY.
3The Orthohealing Center, Los Angeles, CA; University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania- Assistant Professor; Department of Physical Medicine & Rehabilitation and Assistant Director of Sports Medicine Fellowship.
4Musculoskeletal Research International (MRI) and Clinical Research Experts (CRE) Fort Lauderdale, FL; Florida International University, Miami.
*Corresponding Author : Danielle Aufiero
Musculoskeletal Research International (MRI) and Clinical Research Experts (CRE)
Florida International University, Miami, 1004 Avocado Isle, Ft. Lauderdale
FL 33315, Florida
Tel: 954-763-2670
E-mail: avanbemden@hotmail.com
Received: January 02, 2016 Accepted: April 12, 2016 Published: April 15, 2016
Citation: Aufiero D, Sampson S, Onishi K, Bemden VAB (2016) Treatment of Medial and Lateral Elbow Tendinosis with an Injectable Amniotic Membrane Allograft – A Retrospective Case Series. J Pain Relief 5:242. doi:10.4172/2167-0846.1000242
Copyright: © 2016 Aufiero D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

1.1 Background: Epicondylitis is the second most frequently encountered head and upper limb musculoskeletal diagnosis in primary care clinics, with an incidence rate as high as 7/1,000 patients per year. Chronic or recalcitrant epicondylitis- more appropriately termed epicondylosis or elbow tendinosis- is not uncommon and represents a notable set of pathologies which account for lost recreation time, decreased quality of life, and workers compensation claims. A novel non-operative option has recently become available in the form of micronized dehydrated human amniotic/chorionic membrane (mDHACM) allograft. 1.2 Hypothesis: mDHACM allograft is known to be rich in anti-inflammatory cytokines and tissue inhibitors of metalloproteinase and IL-10. It also contains an abundance of growth factors and cytokines. In vivo and in vitro studies have shown reduction in scar tissue. We hypothesize that mDHACM allograft will be a viable treatment option in patients with epicondylosis. 1.3 Study design: Retrospective case series 1.4 Level of evidence: IV 1.5 Methods: Charts were retrospectively reviewed for 10 patients who received mDHACM allograft injections for treatment of medial or lateral epicondylosis.

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