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Toxicology: Open Access
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  • Case Report   
  • Toxicol Open Access,

Treatment of Arsenic Toxicity during APML Treatment in a Pediatric Patient

Ripal Patel1*, Omayma Kishk2, Dimitrios A Savva3 and Adrian Holloway1
1Department of Pediatric Critical Care, University of Maryland Medical Center, Baltimore, USA
2Department of Pediatrics, University of Maryland School of Pharmacy, Baltimore, USA
3Department of Neonatal Critical Care, NewYork-Presbyterian Hospital, New York, USA
*Corresponding Author : Ripal Patel, Department of Pediatric Critical Care, University of Maryland Medical Center, Medical Center , Baltimore, USA, Tel: 410-328-6957, Email: rpatel@som.umaryland.edu

Received Date: Nov 02, 2021 / Accepted Date: Nov 16, 2021 / Published Date: Nov 23, 2021

Abstract

A 17-year-old healthy female was presented with altered mentation after a fall. The workup revealed a new onset of APML. Chemotherapy was initiated. She developed MODS requiring ECMO and CVVHDF. Two days after discontinuation of support, the patient developed acute worsening mentation, emesis, diarrhea, tachycardia, fever, creatinine of 9.58 mg/dL, and prolonged QTc-582, indicating arsenic poisoning from chemotherapy.

Keywords: Arsenic Toxicity;  Emesis;  Mentation;  Hemodialysis

Citation: Patel R, Kishk O, Savva DA, Holloway A (2021) Treatment of Arsenic Toxicity during APML Treatment in a Pediatric Patient. Toxicol Open Access 7:164.

Copyright: © 2021 Patel R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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