Abstract

Diabetic Foot Ulcers (DFUs) represent a chronic and debilitating complication of diabetes mellitus, posing significant challenges to patients and healthcare systems globally. Traditional approaches to DFU management have often fallen short of achieving optimal outcomes, necessitating innovative strategies. Tissue engineering, at the intersection of biology, materials science, and engineering, offers a revolutionary approach to DFU management. This abstract delves into key components of tissue engineering interventions, including advanced biomaterials, cell-based therapies, and bioactive factors, which collectively contribute to creating a conducive microenvironment for tissue regeneration. This abstract explores the transformative role of tissue engineering in diabetic foot ulcer management, presenting a paradigm shift towards regenerative therapies that hold promise for enhanced wound healing and improved clinical outcomes.