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Therapeutic Monoclonal Antibodies Targeting Cytokine Storm: Inclusion as a Future Treatment for the Severe Cases of COVID-19

Shikha Patel1, Bhagawati Saxena2 and Priti Mehta1*
1Department of Pharmaceutical Analysis, Institute of Pharmacy, Nirma University,S.G. Highway, Ahmedabad, 382481, India
2Department of Pharmacology, Institute of Pharmacy, Nirma University, S.G. Highway, Ahmedabad, 382481, India
*Corresponding Author: Priti Mehta, Department of Pharmaceutical Analysis,Institute of Pharmacy, Nirma University, S.G. Highway, Ahmedabad, 382481, India, Email: drpritimehta@nirmauni.ac.in

Received Date: Jul 05, 2021 / Accepted Date: Jul 19, 2021 / Published Date: Jul 27, 2021

Citation: Patel S, Saxena B, and Mehta P. (2021) Therapeutic Monoclonal Antibodies Targeting Cytokine Storm: Inclusion as a Future Treatment for the Severe Cases of COVID-19. J Cytokine Biol 6: 41.

Copyright: © 2021 Patel S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 
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Abstract

Clinical studies have manifested immunotherapeutics as the most propitious for the management of COVID-19 so far. However, the springing up variants of SARS CoV-2 has positioned the role of preventive immunotherapeutics – vaccines in doubt. Even so therapeutic monoclonal antibodies, Tocilizumab – an IL-6 inhibitor and Ravulizumab – a complement protein C5a blocker which are in clinical trial phase –IV are ascertained to be effectual for the COVID-19 cytokine storm and are envisioned to be included as an approved treatment for the severe COVID-19 cases.

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