Abstract

Recently, a number of outstanding review articles covering a wide range of scientific and technological elements of bioanalysis have been published in the literature. Today, it is widely recognised that bioanalysis is essential for characterising novel chemical entities’ pharmacokinetic/pharmacodynamic properties, both at the time of their discovery and during the various stages of drug development that result in their approval for use in the marketplace. This collection examines important bioanalytical standards and how drug research and discovery processes might use them to produce safer, more affordable drugs. It is intended to offer some overarching concepts in this area that will act as the cornerstone of an all-encompassing framework for approaching bioanalysis from the inception (i.e., the identification of a lead molecule) and progressing through various phases of drug development.