ISSN: 2476-2024

Diagnostic Pathology: Open Access
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  • Research Article   
  • Diagn Pathol Open,
  • DOI: 10.4172/2476-2024.1000135

The Synchronicity of Chronic Lymphocytic Leukemia and Multiple Myeloma in a Bone Marrow Biopsy with Therapy Discussion

Zofia Tynski1*, Ikkei Hirama2 and James M. Rossetti3
1Department of Pathology, Clarion Hospital, Hospital Drive, , Clarion, PA 16214, USA
2Department of Family Medicine, Clarion Hospital, Hospital Drive, , Clarion, PA 16214, USA
3Department of Pathology, University of Pittsburgh Medical Center, UPMC Hillman Cancer Center, 5115 Centre Ave, Pittsburgh, PA 15232, USA
*Corresponding Author : Zofia Tynski, Department of Pathology, Clarion Hospital, Hospital Drive, Clarion, PA 16214, USA, Email: zofiatynski@hotmail.com

Received Date: Feb 05, 2018 / Accepted Date: Feb 23, 2018 / Published Date: Feb 28, 2018

Abstract

The coexistence of synchronous chronic lymphocytic leukemia (CLL) and multiple myeloma (MM) in a bone marrow of a patient is a very rare occurrence. To our knowledge, only four publications were reported in the English literature. Herein, we describe a 75 year-old gentleman who presented with fatigue and lethargy of 8 weeks duration. He was found to be anemic, with a mild lymphocytosis, decreased renal function, normal calcium level, and conspicuous M-Spike on serum electrophoresis. Furthermore, trephine bone marrow biopsy demonstrated two distinct hematological malignancies: CLL and MM.

Citation: Zofia T, Ikkei H, Rossetti JM (2018) The Synchronicity of Chronic Lymphocytic Leukemia and Multiple Myeloma in a Bone Marrow Biopsy with Therapy Discussion. Diagn Pathol Open 3: 135. Doi: 10.4172/2476-2024.1000135

Copyright: © 2018 Tynski Z, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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