Abstract

The gingiva and dental follicles in children possess unique regenerative capabilities attributed to the presence of stem cells. Gingival mesenchymal stem cells and dental follicle stem cells exhibit stemness characteristics and have the ability to differentiate into various cell lineages crucial for tissue regeneration. Understanding the gene expression profiles and signaling pathways involved in the stemness of these cells is essential for developing effective regenerative therapies. This article provides an overview of the stemness and gene expression of gingiva and dental follicles in children, highlighting their potential applications in dental treatments and regenerative medicine.