Abstract

The gut-liver axis is a critical physiological system that links the gastrointestinal tract to the liver, playing a significant role in the metabolism and detoxification of various chemicals. Recent research has highlighted the importance of this axis in understanding chemical toxicity, as it influences the bioavailability, metabolism, and overall effects of xenobiotics. This article explores the components and mechanisms of the gut-liver axis, its role in chemical toxicity, and the implications for human health and disease. Understanding the interactions within this axis is essential for developing strategies to mitigate chemical exposure and its associated toxic effects.