Abstract

The study of drug metabolism is crucial in pharmacology for understanding the fate of drugs in the body and optimizing therapeutic outcomes. Microorganisms have emerged as valuable tools in this field, offering unique advantages in simulating, elucidating, and predicting drug metabolism pathways. This abstract explores the diverse applications of microorganisms in drug metabolism research, including microbial transformation, biocatalysis synthesis, drug screening, metabolite profiling, and pharmacokinetic modeling. By harnessing the metabolic capabilities of microorganisms, researchers can gain insights into complex metabolic pathways, identify potential drug candidates, and predict in vivo drug behavior. The use of microorganisms in drug metabolism studies holds promise for advancing pharmacological research and facilitating the development of safer and more effective therapeutics.