The Role of Emerging Therapies in the Management of Pulmonary Fibrosis
*Corresponding Author:Received Date: Nov 01, 2024 / Accepted Date: Nov 30, 2024 /
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Abstract
Pulmonary fibrosis is a progressive and often debilitating lung disease characterized by the thickening and scarring of lung tissue, leading to impaired gas exchange and respiratory failure. This condition can arise from a variety of causes, including idiopathic origins, environmental exposures, autoimmune disorders, and certain medications. The pathophysiology of pulmonary fibrosis involves complex mechanisms of inflammation, epithelial injury, and fibroblast activation, resulting in excessive extracellular matrix deposition. Clinical manifestations typically include progressive dyspnea, chronic cough, and reduced exercise tolerance. Diagnosis relies on a combination of clinical evaluation, imaging studies, and pulmonary function tests. Current therapeutic strategies focus on slowing disease progression and improving quality of life, with emerging treatments targeting specific pathways in fibrosis. Despite advancements in understanding and management, pulmonary fibrosis remains a significant clinical challenge, necessitating ongoing research to uncover effective interventions and improve patient outcomes.