Abstract

Chiral chromatography plays a pivotal role in the advancement of personalized medicine by enabling precise separation and analysis of chiral compounds, which are critical in tailoring treatments to individual patients. This technique facilitates the differentiation of enantiomers, which can exhibit significantly different pharmacological effects, metabolism, and toxicity profiles. By employing chiral chromatography, researchers can ensure the selection of the most effective and least harmful enantiomer for each patient, thus optimizing therapeutic outcomes. Additionally, it supports the development of personalized treatment regimens and dosing strategies by providing detailed insights into the pharmacokinetics and pharmacodynamics of chiral drugs. As personalized medicine continues to evolve, the refinement and application of chiral chromatography will be crucial in advancing individualized healthcare approaches, enhancing drug efficacy, minimizing adverse effects, and ultimately improving patient outcomes.