Abstract

Alkyl groups play a crucial role in organic chemistry and drug design due to their ability to influence molecular stability, reactivity, and biological interactions. These hydrophobic moieties impact pharmacokinetics, drug solubility, and receptor binding, making them fundamental in medicinal chemistry. Their applications extend to structural modifications of bioactive molecules, enhancing drug efficacy and specificity. This article explores the chemical properties of alkyl groups, their role in organic synthesis, and their significance in drug development. Additionally, it discusses recent advancements in alkyl-based drug design and the challenges associated with alkyl modifications.