Journal of Alzheimers Disease & Parkinsonism
Open Access

Mini Review

The Presence of Dementia as one of Diabetic Complications: Hyperglycemia, Hypoglycemia and Glycemic Fluctuation are Associated with the Development of Dementia

Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Japan

*Corresponding Author:

Hideaki Kaneto
Department of Diabetes, Endocrinology and Metabolism
Kawasaki Medical School, 577 Matsushima
Kurashiki 701-0192, Japan
Tel: +81864621111
E-mail: kaneto@med.kawasaki-m.ac.jp

Received date: February 10, 2017; Accepted date: February 16, 2017; Published date: February 23, 2017

Citation: Kaneto H, Kinoshita T, Shimoda M, Kaku K (2017) The Presence of Dementia as one of Diabetic Complications: Hyperglycemia, Hypoglycemia and Glycemic Fluctuation are Associated with the Development of Dementia. J Alzheimers Dis Parkinsonism 7:305. doi:10.4172/2161-0460.1000305

Copyright: © 2017 Kaneto H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

The number of subjects with dementia has been increasing all over the world which has become one of the serious social issues. Mainly, there are two types of dementia; one type is Alzheimer’s disease and another type is vascular dementia. Such dementia is often complicated in elderly subjects with diabetes and thereby it is thought that dementia is one of diabetic complications. There are many possible explanation about the mechanism by which dementia is easily induced in subjects with diabetes. Chronic hyperglycemia and repeated hypoglycemia are closely associated with the onset and/or development of dementia. In addition, the fluctuation of blood glucose level per se is also associated with dementia. In this review article, we would like to describe the current status of dementia and association between dementia and diabetes.

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