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  • Review Article   
  • Cell Mol Biol,
  • DOI: 10.4172/1165-158X.1000217

The Mechanisms and Functions of Transforming Growth Factors-β1 in Tendon Injury

Yujie Li1, Yuanpeng Qiu1, Bin Zhu1, Xueli Liu1, Xinyue Liu1, Sheng Guo2, Chenglong Wang2, Dingxuan Wang1 and Sen Li1,2*
1Institute of Physical Education, Southwest Medical University, Luzhou, Sichuan, China
2Spinal Surgery Department, Hospital (T.C.M) Affiliated to Southwest Medical University, Luzhou, Sichuan, China
*Corresponding Author : Sen Li, Institute of Physical Education, Southwest Medical University, Luzhou, Sichuan, Affiliated Hospital Of Southwest Medical University, Lonngmatan City, Luzhou, City, China, China, Tel: +13679676684, Email: jht187@163.com

Received Date: Sep 21, 2021 / Accepted Date: Oct 22, 2021 / Published Date: Oct 29, 2021

Abstract

Tendon injury is a common injury with slow healing and is usually treated surgically and non-surgically. However, the clinical results are not always satisfactory. Growth factors play an important role in tendon healing, and people increasingly believe that biological intervention can accelerate and improve healing. In recent years, it has been discovered that therapies using bioaugmentation technology have potential benefits and injuries during the healing process of tendon. Transforming growth factors-β1 GF-β1 has been identified as a promising therapeutic target in tendon healing. A lot of evidence shows that exogenous TGF-β1 can accelerate the process of tendon repair. TGF-β1 plays an important role in tendon repair and is a very effective therapeutic agent for tendon diseases. This review summarizes the mechanism and function of TGF-β1 in the repair of tendon injuries.

Citation: Li Y, Qiu Y, Zhu B, Liu X, Liu X, et al. (2021) The Mechanisms and Functions of Transforming Growth Factors-β1 in Tendon Injury. Cell Mol Biol 67: 217. Doi: 10.4172/1165-158X.1000217

Copyright: © 2021 Li Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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