Abstract

This review explores the intricate links among the brain, metabolism, and obesity, elucidating the bidirectional communication pathways that influence energy balance and body weight regulation. Through an examination of neuroendocrine signaling, hypothalamic control mechanisms, and the impact of obesity on brain structure and function, this study provides insights into the complex interplay between the central nervous system and metabolic processes. Understanding these connections is vital for unraveling the neurobiological underpinnings of obesity and developing targeted interventions for its prevention and management.