Abstract

Metal-on-metal hip implants have raised concerns regarding the release of metal ions into the bloodstream and associated complications. Monitoring metal ion levels in patients with MoM hips is crucial for early detection of implantrelated issues. Two common sample types used for metal ion measurement are plasma and whole blood. This article explores the interchangeability of plasma and whole blood metal ion measurement and their significance in monitoring patients with MoM hip implants. The discussion highlights the advantages and limitations of both measurement methods and emphasizes the need for standardized guidelines and further research to guide clinical decision-making.