Review Article
The Influence Of Postoperative Analgesia On The Perioperative Immune Function In Cancer Patients
Chen B and Liu H* | |
Department of Anesthesia, Chongqing Cancer Institute, Chongqing, China | |
Corresponding Author : | Dr Hongliang Liu Department of Anesthesia Chongqing Cancer Institute, Chongqing, China Tel: 86-23-6507-5687 Fax: 86-23-6531-1341 E-mail: Liuhl75@163.com |
Received April 24, 2014; Accepted May 22, 2014; Published May 24, 2014 | |
Citation: Chen B and Liu H (2014) The Influence of Postoperative Analgesia on the Perioperative Immune Function in Cancer Patients. J Pain Relief 3:147. doi: 10.4172/2167-0846.1000147 | |
Copyright: © 2014 Chen and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
Abstract
Postoperative pain significantly suppresses cell-mediated immunity (CMI). Effective postoperative analgesia can improve CMI and reduce cancer recurrence and metastasis. This article reviews the influence of different analgesic agents and techniques on perioperative immune function and long-term outcome of cancer patients, and the underlying mechanisms are described in detail.