ISSN: 2572-4983

Neonatal and Pediatric Medicine
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  • Mini Review   
  • Neonat Pediatr Med 2015, Vol 1(1): S1002
  • DOI: 10.4172/2572-4983.1000S1002

The Increase of AMP-activated Protein Kinase during Physical Activities can Reduce Symptoms of Autistic Children

Bakouie F1*, Darvishi A2, Bahrami S2 and Gharibzadeh S1
1Institute for Cognitive and Brain Sciences (ICBS), Shahid Beheshti University, Iran
2Student’s Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran
*Corresponding Author : Bakouie F, Institute for Cognitive and Brain Sciences (ICBS), Shahid Beheshti University, Iran, Tel: (009821) 2403041, Email: f_bakouie@sbu.ac.ir

Received Date: Oct 26, 2015 / Accepted Date: Dec 08, 2015 / Published Date: Dec 15, 2015

Abstract

Autism spectrum disorders (ASD) are one of the neurodevelopmental disorders. About one-five of children diagnosed with ASD have regression autism. Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is precisely control the balance of ATP metabolism in mitochondria, the organelle that show dysfunction in regressive autism. Studies have shown that this sensor kinase can be effective in axonal growth. It has been suggested that exercise is one of the most powerful factors that increase mitochondrial activity and the amount of AMPK. Above the mentioned, we hypothesized that the physical activities can increase mitochondrial activity and reduce the symptoms of autistic children.

Keywords: Autism spectrum disorders; Adenosine monophosphate; Threonine protein kinase

Citation: Bakouie F, Darvishi A, Bahrami S, Gharibzadeh S (2015) The Increase of AMP-activated Protein Kinase during Physical Activities can Reduce Symptoms of Autistic Children. Neonat Pediatr Med 1: S1002. Doi: 10.4172/2572-4983.1000S1002

Copyright: © 2015 Bakouie F, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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