Abstract

Acute ischemic stroke remains a significant cause of morbidity and mortality worldwide. Endovascular thrombectomy has emerged as a primary treatment modality, offering improved outcomes for select patients. However, recent studies have highlighted the potential detrimental effects of global hyperperfusion following successful thrombectomy, complicating prognostic assessments. This article reviews the current literature to elucidate the association between global hyperperfusion and prognosis post-thrombectomy in acute ischemic stroke patients. We discuss the mechanisms underlying hyperperfusion injury, the clinical implications, and potential strategies for mitigating its adverse effects