Abstract

Objective: This study aims to evaluate the efficacy of platelet-rich plasma (PRP) therapy in the treatment of chronic Achilles tendinopathy, focusing on pain reduction, functional improvement, and patient-reported outcomes.

Background: Chronic Achilles tendinopathy is a common musculoskeletal disorder characterized by pain, swelling, and impaired function of the Achilles tendon. Traditional treatments such as rest, physical therapy, and antiinflammatory medications may provide symptomatic relief but often fail to resolve symptoms completely. PRP therapy has emerged as a promising alternative, utilizing autologous growth factors to promote tissue healing and reduce inflammation at the tendon injury site.

Methods: A systematic review of clinical trials and prospective studies investigating the use of PRP for chronic Achilles tendinopathy was conducted. Studies reporting on pain scores, functional outcomes (e.g., activity level, range of motion), tendon healing, and patient satisfaction were included. The efficacy of PRP was compared to placebo or traditional treatments to assess its relative effectiveness.

Results: Preliminary findings suggest that PRP therapy offers beneficial effects in the management of chronic Achilles tendinopathy. Studies indicate significant improvements in pain relief, functional outcomes, and patientreported measures following PRP injections. The regenerative properties of PRP appear to promote tendon healing, reduce tendon thickness, and enhance tissue repair compared to conventional treatments. However, variability in study design, PRP preparation protocols, and outcome measures necessitates further investigation to establish standardized guidelines and optimal treatment protocols.

Conclusion: Platelet-rich plasma therapy shows promise as an effective treatment option for chronic Achilles tendinopathy, offering potential benefits in pain reduction, functional improvement, and tendon healing. Continued research efforts are essential to elucidate the mechanisms of action, optimize treatment protocols, and determine longterm outcomes to support its integration into clinical practice.