Abstract

One in every four to five pregnancies is affected by pregnancy problems, such as gestational diabetes, hypertension, foetal growth restriction, and premature delivery. There is growing evidence that these difficulties are accompanied with an increase in the generation of reactive oxygen species. Although the precise methods by which reactive oxygen species contribute to pregnancy difficulties are not fully known, they may have a causative role in disease pathophysiology given that they are agents that cause cell stress. Pregnancy-related exposures may enhance the creation of reactive oxygen species since several environmental and lifestyle variables and exposures have been shown to affect their production. This review's goal is to give a thorough summary of the endogenous and external exposome components that control reactive species in complex, healthy organism’s pregnancies in order to lessen unfavourable pregnancy outcomes; we also describe dietary strategies that attempt to reduce reactive species.