Abstract

Keratitis and Dry Eye Syndrome (DES) are two interrelated ocular conditions that significantly impact patients' visual health and quality of life. This review explores the connection between keratitis and DES, focusing on the pathophysiological mechanisms, clinical manifestations, and therapeutic approaches. Keratitis, an inflammation of the cornea, often arises as a complication of untreated or poorly managed DES. The chronic deficiency in tear production and/or tear film instability in DES leads to corneal epithelial damage, which predisposes the eye to infection, inflammation, and subsequent keratitis. In turn, keratitis exacerbates the symptoms of DES, creating a vicious cycle of ocular surface disease. Recent advances in diagnostic techniques have improved the ability to detect early signs of both conditions, allowing for more targeted interventions. Treatment strategies emphasize the importance of addressing both the underlying tear film dysfunction in DES and the inflammatory processes in keratitis to prevent long-term damage to the cornea. Understanding the intricate relationship between keratitis and DES is crucial for developing comprehensive management plans that enhance patient outcomes and preserve ocular health.