The Configuration Robustness of a Functional Genome is Revealed by Single-Chromosome Fission Yeast Models
*Corresponding Author: Jin-Qiu Zhou, State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China, Email: jinquilk@uyt.comReceived Date: Sep 03, 2022 / Published Date: Sep 28, 2022
Citation: Zhou JQ (2022) The Configuration Robustness of a Functional Genome is Revealed by Single-Chromosome Fission Yeast Models. J Cell Mol Pharmacol 6: 134.DOI: 10.4172/jcmp.1000134
Copyright: © 2022 Zhou JQ. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
The physical units that house genetic information are called chromosomes. Chromosome counts in eukarya differ amongst organisms; for example, the male ant Myrmecia pilosula has one chromosome, whereas the fern Ophioglossum reticulatum has hundreds Chromosome number reduction by fusion happened during the evolution of apes to humans, as evidenced by the strong resemblance between human chromosome 2 and two ancestral ape chromosomes 2A and 2B. It is unknown if changes in chromosomal counts over time in a particular species encourage speciation and offer adaptive advantages. Various chromosomes In an interphase nucleus, chromosomal territories (CTs) often occupy distinct areas.It is recognised that chromosomal architecture and spatial structure regulate gene expression and define cellular processes [1-15]. The tolerance for chromosome configuration changes, both organic and synthetic, varies. Thai Fea’s muntjacs (Muntiacus feae) exhibit 2n = 12, 13 (female), or 14 (female and male) .The karyotypes of the Indian muntjac (M. muntjak vaginalis) and Chinese muntjac (M. reevesi), two closely related species, are noticeably different.