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Hindi Synthesis, characterization and application of novel bio-polymeric Schiff base from chitosan and 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4- carboxaldehyde
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Copyright: © 2018 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Schiff base of chitosan and 5-chloro-3-methyl-1-phenyl-1H-pyrazole- 4-carboxaldehyde was prepared by reaction of chitosan with 5- chloro-3-methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde in the presence of acetic acid as a solvent. Some reaction parameters have been investigated such as temperature effect, time effect and mol ratio and optimize the product. The product has been ascertained by FT- IR spectroscopy. Antifungal activities of the Schiff base against Aspergillums' Niger (A. Niger) and Penicillium were measured through the agar well diffusion method.
