Abstract

Molluscs exhibit remarkable adaptability to intertidal environments, which are characterized by fluctuating salinity, temperature, and oxygen levels. This review explores the intricate role of microRNAs (miRNAs) in modulating the neuroendocrine-inflammation pathway, shedding light on their significance in facilitating intertidal adaptation among molluscs. Through a comprehensive analysis of recent research findings, this article discusses the regulatory mechanisms underlying miRNA-mediated synergy within the neuroendocrine-inflammation pathway and its implications for molluscan adaptation to intertidal habitats. Furthermore, it presents key insights into the potential applications of miRNA-based strategies for conservation and management of molluscan populations in the face of environmental challenges