Abstract

Giant Cell Tumors of Bone (GCTBs) present unique challenges in orthopedic oncology due to their locally aggressive nature and propensity for recurrence. This article reviews current surgical techniques and prognostic factors critical for managing GCTBs, emphasizing recent advancements and outcomes in treatment. Surgical approaches include curettage with adjuvant therapies and en-bloc resection, aimed at achieving oncological control while preserving limb function. Prognostic factors such as radiological features and histopathological characteristics guide treatment decisions, influencing surgical strategies and patient outcomes.