Review Article
Supplementation of Magnesium in Pregnancy
Ludwig Spätling1*, Hans-Georg Classen2, Klaus Kisters3, Ursula Liebscher4, Ragnar Rylander5, Wolfgang Vierling6, Bodo von Ehrlich7and Jürgen Vormann8*1Department of Obstetrics and Gynaecology, Klinikum Fulda, Fulda, Germany
2Institute of Pharmacology and Toxicology, University Hohenheim, Stuttgart, Germany
3Medical Clinic I, St. Anna Hospital, Herne, Germany
4SHO Mineralimbalancen, Berlin, Germany
5BioFact, Environmental Health Research Center, Lerum, Sweden
6Institute of Pharmacology and Toxicology, Technical University Munich, Germany
7Internal Medicine Clinic, Kempten, Germany
8Institute for Prevention and Nutrition, Ismaning/Munich, Germany
- *Corresponding Author:
- Spätling L
Institute for Prevention and Nutrition
Adalperostrasse 37, D-85737 Ismaning/Munich, Germany
Tel: 498955267989
E-mail: vormann@ipev.de
Received date: February 02, 2017; Accepted date: February 23, 2017; Published date: February 28, 2017
Citation: Spätling L, Classen HG, Kisters K, Liebscher U, Rylander R, et al. (2017) Supplementation of Magnesium in Pregnancy. J Preg Child Health 4:302. doi:10.4172/2376-127X.1000302
Copyright: © 2017 Spatling L, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Abstract
Although the relevance of magnesium in obstetrics has been known for a long time and its effect in many diseases is well documented, oral magnesium supplementation during pregnancy is a subject of discussion. The evaluation of the variety of studies regarding magnesium supplementation in pregnancy clearly shows positive effects of oral substitution, in contrast to the Cochrane analysis. In addition to the needs of the growth of the fetus and the maternal tissue, elevated renal magnesium excretion is a reason for an increased magnesium requirement during pregnancy. This enhanced renal loss leads to a decreased serum magnesium concentration, which can also be recognized in the myometrium.