Abstract

Diabetic renal disease, also known as diabetic nephropathy, is a progressive kidney condition that arises as a complication of diabetes mellitus. This abstract provides an overview of the study of diabetic renal disease, including its pathogenesis, risk factors, diagnosis, and management strategies. The pathogenesis of diabetic nephropathy involves multiple mechanisms, including chronic hyperglycemia, oxidative stress, inflammation, and activation of the renin-angiotensin-aldosterone system. Several risk factors, such as poor glycemic control, hypertension, and genetic predisposition, contribute to the development and progression of the disease. Diagnosis involves monitoring urinary albumin excretion, blood pressure, and renal function. Management strategies focus on lifestyle modifications, pharmacological interventions, and control of cardiovascular risk factors. Emerging therapies, including targeted agents and regenerative medicine approaches, offer potential avenues for future treatments. Understanding the complexities of diabetic renal disease is crucial for early detection, intervention, and improving outcomes for affected individuals.