Abstract

Nanoparticles have garnered significant attention in various fields owing to their unique properties and wide-ranging applications. In recent years, there has been growing interest in utilizing plant oils as sustainable starting materials for nanoparticle synthesis. Among the various techniques available, triazolinedione-ene chemistry has emerged as a versatile and efficient method for fabricating chemically crosslinked nanoparticles. This article provides an indepth exploration of the synthesis process, highlighting its simplicity, scalability, and potential applications. However, conventional methods for nanoparticle synthesis often rely on non-renewable resources and complex procedures. In recent years, there has been increasing interest in developing sustainable approaches for nanoparticle fabrication. One promising method involves the use of plant oils as renewable starting materials in conjunction with triazolinedioneene chemistry. This synthesis route offers a straightforward and efficient means of producing chemically crosslinked nanoparticles with tailored properties. Here, we present an overview of this method, highlighting its simplicity, scalability, and potential applications. By harnessing the reactivity of triazolinedione compounds with carbon-carbon double bonds present in unsaturated fatty acids, this approach enables the formation of stable nanoparticle networks. The resulting nanoparticles exhibit desirable characteristics such as biocompatibility, tunable morphology, and surface functionality, making them suitable for a wide range of applications including drug delivery, catalysis, coatings, and materials science. Furthermore, the use of renewable plant oils contributes to the sustainability of the synthesis process. While challenges exist in characterization and scalability, ongoing research efforts aim to optimize synthesis parameters and explore new applications, paving the way for greener and more sustainable nanoparticle synthesis methods.