Abstract

Oncology treatment planning has traditionally relied on standardized protocols designed to guide therapeutic decisions across patient populations. However, with advances in molecular biology, genomics, and personalized medicine, there is a growing shift towards individualized care. This paper explores the paradigm shift from onesize- fits-all treatment approaches to more tailored, patient-specific strategies that consider genetic, environmental, and lifestyle factors. We examine how precision medicine is influencing clinical decision-making, the integration of biomarker-driven therapies, and the challenges and opportunities in implementing personalized treatment plans. The goal is to highlight the importance of balancing evidence-based guidelines with personalized care to improve treatment outcomes and patient quality of life in oncology.