Abstract

The most important prognostic factor for oral carcinomas is cervical metastasis. Cervical metastasis is influenced by clinical and histological variables, but recent years have seen a significant increase in the study of molecular factors.

Aim: This study's objective is to examine the Cyclin D1's potential role as a risk factor for cervical metastases.

Materials and Methods: In 45 oral cancer patients who were being treated by the author of this research, Cyclin D1 expression was assessed, and a relationship between such a substance and metastasis was discovered. The stereological approach was used to confirm the existence of cytokine D1. Analysis and correlation of metastasisrelated clinical and histological traits has been done.

Result: Although Cyclin D1 expression was observed in 15 patients, it wasn't linked to any clinical or histological characteristics that indicated the presence of metastases. Such a finding suggests that Cyclin D1 is a separate protein. Clinical staging and vascular embolisation have been the most significant prognostic factors in relation to the development of metastases.

Conclusion: Despite being independent, Cyclin D1 is not linked to cervical metastases; nevertheless, staging and vascular embolisation.