Abstract

Spectrophotometric determination of Bromhexine Hydrochloride in pure and pharmaceutical forms is an essential analytical technique in pharmaceutical analysis. This article provides an overview of the principles, methods, and applications of spectrophotometric analysis for Bromhexine HCl. The article discusses the underlying principles of spectrophotometry, including the Beer-Lambert law, and highlights the various spectrophotometric methods employed for Bromhexine HCl determination, such as UV-Visible spectrophotometry, derivative spectrophotometry, and the H-point standard addition method. The importance of method validation, sample preparation, and wavelength selection is emphasized. The discussion also includes challenges and limitations associated with spectrophotometric analysis of Bromhexine HCl, including interferences and sample degradation. Overall, spectrophotometric determination of Bromhexine HCl plays a vital role in quality control, dosage form analysis, and pharmacokinetic studies, ensuring the accurate determination of Bromhexine HCl content and contributing to the safety and efficacy of Bromhexine HClbased medications.