Specific Quality of Sensation Derived from the Pain-Spots
Received Date: Nov 24, 2022 / Published Date: Dec 22, 2022
Abstract
The most common type of cannabinoid is the tetra-hydrocannabinol, which is one of the major psychoactive components isolated from Cannabis sativa. Cannabinoids can bind to Gi-protein coupled cannabinoid type 1 receptors, which is highly expressed in the pre- and post-synaptic in brain and spinal cord, as well as the Gi-proteincoupled cannabinoid type 2 receptors that is predominantly located in the immune system. The activation of CB1 and CB2 inhibits the formation of intracellular cAMP, hence leading to a tremendous reduction of the excitatory effect within the neurons.
Keywords: Cannabinoid; Pain sensation; Receptors; Neurokinin;Spinal cord; Pain pathway
Citation: Cain JG (2022) Specific Quality of Sensation Derived from the Pain- Spots. J Pain Relief 11: 474. Doi: 10.4172/2167-0846.1000474
Copyright: © 2022 Cain JG. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Share This Article
Recommended Journals
Open Access Journals
Article Tools
Article Usage
- Total views: 566
- [From(publication date): 0-2022 - Jul 17, 2024]
- Breakdown by view type
- HTML page views: 422
- PDF downloads: 144
