Abstract

Our skin is exposed daily to substances; many of these are neutral and safe but others are potentially harmful. In order to estimate the degree of toxicity and damage to skin tissues when exposed to harmful substances, skin toxicology studies are required. If these studies are coupled with suitably designed mathematical models, they can provide a powerful tool that allows appropriate interpretation of data. This work reviews mathematical models that can be employed in skin toxicology studies. Areas covered: Two types of mathematical models and their suitability for assessing skin toxicology are covered in this review.