Significance of Breslow Density as a New Prognostic Feature in Cutaneous Melanoma
Received Date: Jun 03, 2022 / Published Date: Jul 06, 2022
Abstract
Breslow density is a novel biomarker for the assessment of tumor load in cutaneous melanoma cases. Breslow density is measured in the deepest invasive area that Breslow thickness was measured in the formalin-fixed paraffin-embedded sections. The determination of Breslow density is a simple, low-cost, and reproducible method. Interobserver compliance and accuracy rates are very high. Studies in the literature have reported that high Breslow density is associated with poor prognosis and is a predictive biomarker of short survival. Considering the prognostic and predictive value of Breslow density and the strong interobserver agreement, documentation of Breslow density in the pathology report would contribute to the prediction of the prognosis.
Keywords: Breslow density; Biomarker; Melanoma; Prognosis
Citation: Secinti IE, Gursoy D, Ozgur G, Dogan E (2022) Significance of Breslow Density as a New Prognostic Feature in Cutaneous Melanoma. Diagnos Pathol Open 7:205 Doi: 10.4172/2476-2024.7.3.205
Copyright: © 2022 Secinti IE, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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