Abstract

In the Edo period of Japan, drinking carp blood was well known
to the people as a folk remedy for tuberculosis. This bacteriostatic
activity of blood is suggested to exist some antimicrobials in carp
blood. We isolated a high-purity carp glycophorin (membrane protein
containing sialo-oligosaccharide) from carp red blood cell (RBC)
membranes using the lithium diiodosalicylate (LIS)-phenol method
and streptomycin treatment.