Risk Prognosis Model Construction and Model Effectiveness Evaluation of Bone Cancer
Received Date: May 01, 2023 / Published Date: May 30, 2023
Abstract
Using a specific whole-genome expression profile and genes related to epithelial-mesenchymal transition (EMT), the purpose of this study was to create a weighted co-expression network and a BC prognosis evaluation system; thus providing the foundation and reference for determining the risk of metastatic breast cancer (MBC) spreading to the bone as a prognostic factor. Four quality articulation datasets of countless examples from GEO were downloaded and consolidated with the dbEMT data set to screen out EMT differentially communicated qualities (DEGs). A weighted coexpression network for EMT DEGs was constructed using the GSE20685 dataset as a training set, and the hub genes with the greatest relevance to metastasis were chosen.
Citation: Yuan L (2023) Risk Prognosis Model Construction and Model Effectiveness Evaluation of Bone Cancer. J Orthop Oncol 9: 201. Doi: 10.4172/2472-016X.100201
Copyright: © 2023 Yuan L. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
