Abstract

Rhabdomyosarcoma (RMS) is a rare but aggressive soft tissue sarcoma that primarily affects children and young adults, characterized by the malignant transformation of skeletal muscle cells. Despite advances in treatment, outcomes for patients with RMS can vary based on tumor location, histological subtype, and the presence of metastases at diagnosis. Multidisciplinary care plays a crucial role in optimizing treatment success for RMS patients. This approach involves the integration of surgical, chemotherapy, radiation therapy, and supportive care interventions tailored to the individual patient’s needs. Surgical resection remains a primary treatment modality, often combined with chemotherapy and radiation to reduce the risk of recurrence and metastasis. Additionally, advancements in molecular diagnostics and precision medicine offer the potential for personalized treatment strategies that improve prognostic accuracy and therapeutic efficacy. The involvement of various specialists—including oncologists, radiologists, pathologists, surgeons, and palliative care teams—is essential in providing comprehensive care that addresses the clinical, emotional, and social needs of patients and their families. This review highlights the importance of a collaborative, multidisciplinary approach in the management of rhabdomyosarcoma, emphasizing the need for coordinated care to enhance patient outcomes and improve long-term survival.