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Hindi Revolutionizing Neurological Disorder Therapies Nucleic Acid Polymer Complexes for Precision Drug Delivery and Targeted Treatment
*Corresponding Author:Received Date: Nov 01, 2024 / Published Date: Nov 30, 2024
Copyright: © 0 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
The treatment of neurological disorders has long been hindered by challenges such as the blood-brain barrier (BBB), limited bioavailability, and the need for highly targeted therapeutic delivery. Nucleic acid polymer complexes present a transformative approach to overcoming these obstacles, enabling precision drug delivery and targeted treatment for various neurological conditions. These complexes, composed of polymers and nucleic acids (e.g., DNA, RNA), offer enhanced stability, controlled release, and the potential for personalized therapies. By facilitating the transport of therapeutic agents directly to the brain, nucleic acid polymer complexes can significantly improve the efficacy and safety of treatments for conditions like Alzheimer’s disease, Parkinson’s disease, and genetic neurological disorders. This paper explores the underlying mechanisms of nucleic acid polymer complexes in drug delivery systems, their advantages in overcoming BBB limitations, and their integration with gene therapy, RNA-based therapies, and small molecule drugs. Through precision medicine strategies, these complexes have the potential to revolutionize the landscape of neurological disorder therapies, improving patient outcomes and providing more effective, individualized treatments.
