Reliability of Core Needle Biopsy in Diaqnosis of Malignant Bone Tumours
*Corresponding Author: Hassan Elbahri, Department of orthopaedic oncology, International University of Africa (IUA), Khartoum, Sudan, Tel: +249912224183, Email: hssnbahari0@gmail.com
Copyright: © 2021 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Background: Compared to open biopsy core needle biopsy is less invasive technique with fewer complications; however its reliabity in reaching accurate diagnosis is still questionable. The aim of this study is to evaluate the accuracy of core needle biopsy in diagnosis of malignant bone tumours.
Material and Method: This is a retrospective analytical cross sectional study on 152 patients underwent core needle biopsy and followed by definitive surgery during the period of 2016- 2017 at Ibrahim Malik Teaching Hospital, Khartoum, Sudan. The needle biopsies were assessed for sensitivity, specificity, predictive positive value, and predictive negative value.
Results: A final diagnosis was not reached in 7/152 patients (4.7%) with an overall sensitivity of 96.2 % (104\108), and specificity of 93.1% (41\44), positive predictive value of 97.1% (104\107), negative predictive value of 91.1% (41\45). No complications due to core needle biopsy were noted.
Conclusion: Core needle biopsy is a reliable method for reaching the final diagnosis in malignant bone tumours with fewer complications. It could be adopted confidently in clinical practice instead of the open biopsy method.