Recurrent Pelvic Aneurysmal Bone Cyst Treated With Doxycycline: A Case Report
*Corresponding Author: Dr. T Kyle Summers MD, University of South Alabama, United States, Tel: 2512831686, Email: tsummers@health.southalabama.eduReceived Date: Dec 29, 2022 / Accepted Date: Jan 24, 2023 / Published Date: Jan 30, 2023
Citation: Summers TK, Austin Bettridge MSIV, Nimityongskul P (2023) Recurrent Pelvic Aneurysmal Bone Cyst Treated With Doxycycline: A Case Report. J Orthop Oncol 9: 188.
Copyright: © 2023 Summers TK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract
Background: Aneurysmal bone cysts (ABCs) are locally aggressive, non-cancerous bone lesions that are rare, most commonly occur in children (75% of patients are < 20 yrs 1), and typically continue to spread until treated. They have a high risk of recurrence [1].
Methods: We present an 11-year-old female with a recurrent ABC of the pelvis, involving the right pubic ramus, ischium and medial wall of the acetabulum. She was treated initially with curettage and bone grafting but was discovered to have recurred at two-year follow-up. She was successfully treated with repeat curettage with iliac bone grafting and doxycycline as a sclerosing agent.
Results: At two and three-month follow up visits the patient continues to ambulate well, and radiographs demonstrate healing with successful graft incorporation and no sign of recurrence.
Conclusion: At the time of this publication, there were no reports detailing the use of doxycycline as a sclerosing agent for recurrent pelvic ABCs as extensive as the case presented here. However, doxycycline has been recently reported as efficacious in the treatment of other recurrent ABCs, primarily through percutaneous administration.