Abstract

Patients with cirrhosis are more likely to be frail and have poorer health outcomes before and after liver transplantation. Physical deconditioning often lags behind the rapid and complete recovery of hepatic synthetic function and resolution of portal hypertensive complications following transplantation. Frailty and sarcopenia have been shown to worsen six to twelve months after liver transplantation, with only a modest improvement thereafter, according to studies. Transplant recipients’ recovery from a major surgery that depleted their physiologic reserve is hindered by persistent physical deconditioning. As a result, if we want to keep improving transplant care in the future, we need specific interventions to make people less frail