Abstract

Radiographic evaluation plays a crucial role in the diagnosis and management of primary bone tumors. This article provides an in-depth discussion on the radiographic features of primary bone tumors and the differential diagnosis process. Key features assessed on radiographs include lesion location, margins, cortical integrity, periosteal reaction, matrix mineralization, soft tissue involvement, bone destruction, and size/growth pattern. Understanding these features is essential for distinguishing between benign and malignant lesions and guiding further diagnostic workup. The differential diagnosis encompasses a broad spectrum of benign and malignant entities, as well as non-neoplastic conditions. Effective interpretation of radiographic findings requires integration with clinical history and other diagnostic data, leading to timely diagnosis and appropriate treatment selection for patients with primary bone tumors