Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi Research Article
Prostate Volume in Patients Undergoing Primary Surgical or Radiotherapeutic Management of Localized Adenocarcinoma: Implications for Design of Minimally Invasive Imaging and Treatment Devices for the Prostate
| Davis BJ1*, Leenstra JL1, Wilson TM2, Mynderse LA2, Solhjem MC3, Herman MG1, Hillman DW1, Allen-Ziegler KL4, Cheville JC5, King BF6 and Holmes III DR7 | |
| 1Department of Radiation Oncology (J.L.L., B.J.D., M.C.S., M.G.H.), Mayo Clinic, Rochester, Minnesota, USA | |
| 2Department of Urology (T.M.W., L.A.M.), Mayo Clinic, Rochester, Minnesota, USA | |
| 3Department of Radiation Oncology, The Oregon Clinic, Portland, Oregon, USA | |
| 4Division of Biomedical Informatics and Biostatistics (D.W.H., K.L.A.-Z), Mayo Clinic, Rochester, Minnesota, USA | |
| 5Department of Laboratory Medicine and Pathology (J.C.C.), Mayo Clinic, Rochester, Minnesota, USA | |
| 6Department of Radiology (B.F.K.), Mayo Clinic, Rochester, Minnesota, USA | |
| 7Department of Physiology and Biomedical Engineering (D.R.H), Mayo Clinic, Rochester, Minnesota, USA | |
| Corresponding Author : | Davis BJ Department of Radiation Oncology (J.L.L.,B.J.D., M.C.S., M.G.H.) Mayo Clinic, Rochester, Minnesota, USA Tel: 507-284-2511 E-mail: davis.brian@mayo.edu |
| Received May 01, 2014; Accepted May 2, 2014; Published June 06, 2014 | |
| Citation: Davis BJ, Leenstra JL, Wilson TM, Mynderse LA, Solhjem MC, et al. (2014) Prostate Volume in Patients Undergoing Primary Surgical or Radiotherapeutic Management of Localized Adenocarcinoma: Implications for Design of Minimally Invasive Imaging and Treatment Devices for the Prostate. OMICS J Radiol S1:001. doi: 10.4172/2167-7964.S1-001 | |
| Copyright: © 2014 Davis BJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | |
Abstract
Introduction: The objective of this study was to collect and analyze prostate volumetric data from different patient cohorts treated for localized prostate cancer. These data were examined with respect to the design of minimally invasive treatment devices for localized prostate cancer.
Methods: Among 700 patients with prostate cancer (stages T1a-T3c), 342 had radical retropubic prostatectomy (RRP) specimens submitted for whole mounting; 308 received permanent prostate brachytherapy and underwent transrectal ultrasonography (TRUS); and 50 received external beam radiotherapy with computed tomographic (CT)- based 3-dimensional treatment planning. Analysis included cumulative histograms, descriptive statistics, and statistical comparisons of median height, width, length, and volume.
Results: Median prostate dimensions (in millimeters) and volumes (in cubic centimeters) were as follows: Height by RRP was 30; TRUS prolate, 33; TRUS planimetry, 35; and CT, 42. Width by RRP was 47; TRUS prolate, 50; TRUS planimetry, 51; and CT, 51. Length by RRP was 42; TRUS prolate, 49; TRUS planimetry, 45; and CT, 41. Volume by RRP was 32; TRUS prolate, 41; TRUS planimetry, 43; and CT, 45.
Conclusions: Although median TRUS and CT volumes were similar (41-45 cm3), median RRP volume was 9 to 13 cm3 less. Of the cases examined, 75% would be encompassed by an imaging device with an azimuthal field of view of 48 to 55 mm and 95% by a device with a length of 54 to 63 mm.
