ISSN: 2376-127X

Journal of Pregnancy and Child Health
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Promoting Of Ovarian Cancer of Role and Hallmarks of Sp1

Angel Yadav*
Department of Obstetrics and Gynaecology, University of British Columbia, Canada
*Corresponding Author : Angel Yadav, Department of Obstetrics and Gynaecology, University of British Columbia, Canada, Email: AngelYadav765@gmail.com

Received Date: Feb 02, 2023 / Accepted Date: Feb 28, 2023 / Published Date: Feb 28, 2023

Abstract

A late diagnosis, intrinsic drug resistance, and rising interest in discovering novel DNA binding and transcription factor agents as potential therapies in treating ovarian and other gynaecological cancers are all contributing factors to the poor prognosis of ovarian cancer. A deeper knowledge of Sp1's role in the initiation and progression of human cancer is still needed, but it is clear from several prior publications that Sp1 controls the expression of many cellular genes. Sp1 has been discovered to have a dual role, activating and suppressing cellular genes that could otherwise become oncogenes or engage in biological processes like proliferation, differentiation, DNA damage response, apoptosis, and angiogenesis. In fact, there are indications that Sp1 has identical protein variants known as Sp2 and Sp3 support Sp1 in promoting the growth of tumour cells.

Citation: Yadav A (2023) Promoting Of Ovarian Cancer of Role and Hallmarks ofSp1. J Preg Child Health 10: 575.

Copyright: © 2023 Yadav A. This is an open-access article distributed under theterms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.

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