Prognostic Factors for Mortality in Hospitalized Stroke Patients with COVID-19: A Retrospective Cohort Study
Received Date: Apr 01, 2023 / Published Date: May 02, 2023
Abstract
Patients with stroke are at increased risk of poor outcomes of COVID-19, yet data on prognostic factors of COVID-19 mortality in this population remained limited. In this multicenter retrospective cohort study, we investigated the clinical characteristics of hospitalized patients with COVID-19 and pre-existing stroke and assessed the risk factors for in-hospital mortality. Patients with COVID-19 and a history of stroke between January 1 and September 30, 2022, were included. Clinical data were extracted from electronic medical records. Univariate
and multivariable logistic regression analyses were conducted to identify the risk factors for in-hospital mortality. This study included 282 patients, comprising 57 (20.2%) who died (nonsurvivors) and 225 (79.8%) survivors. Multivariable analyses indicated that higher in-hospital mortality was associated with advanced age (>80 years; odds ratio [OR]: 3.46; 95% Confidence Interval [CI]: 1.70-7.03), residence in a long-term care facility (OR: 2.60; 95% CI: 1.70-5.70), a higher baseline modified Ranking scale score (OR: 1.53; 95% CI: 1.07-2.19), lymphopenia (OR: 3.12; 95% CI: 1.53-6.35), and elevated serum creatinine (OR: 3.86; 95% CI: 1.80-8.26) in patients with COVID-19 and pre-existing stroke.
Keywords: COVID-19; Mortality; Stroke; Risk factors
Citation: Lu KH, Chang TC, Lai CC, Kan WC, Ho CH, et al. (2023) Prognostic Factors for Mortality in Hospitalized Stroke Patients with COVID-19: A Retrospective Cohort Study. J Infect Dis Ther 11: 540. Doi: 10.4172/2332-0877.1000540
Copyright: © 2023 Lu KH, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
